• 100. Shan L and Chen LL*. Unveiling the mystery of nuclear RNA homeostasis. Cell Stem Cell, May 2nd, 2024.
  • 99. Feng X, Jiang B, Zhai SN, Liu CX, Wu H, Zu BQ, Wei MY, Wei J, Yang L and Chen LL*. Circular RNA aptamers ameliorate Alzheimer’s disease-relevant phenotypes by targeting PKR. bioRxiv, 2024.
  • 98. Cao SM, Wu H, Yuan GH, Pan YH, Zhang J, Liu YX, Li SQ, Xu YF, Wei MY, Yang L and Chen LL*. Altered nucleocytoplasmic export of adenosine (A)-rich circRNAs by PABPC1 contributes to neuronal function. Mol Cell, in press.
  • 97. Yang LZ, Min YH, Liu YX, Gao BQ, Liu XQ, Huang YK, Wang HF, Yang L, Liu Z and Chen LL*. CRISPR array-mediated imaging of non-repetitive and multiplex genomic loci in living cells. Nat Methods, in press.
  • 96. Zhang L, Cao SM, Wu H, Yan M, Li J* and Chen LL*. A CRISPR/RfxCas13d-mediated strategy for efficient RNA knockdown in mouse embryonic development. Sci China Life Sci, in press.
  • 95. Guo SK, Liu CX, Xu YF, Wang X, Nan F, Huang YK, Li SQ, Nan S, Li L, Kon E, Li C, Wei MY, Su R, Wei J, Peng SG, Ad-El N, Liu JQ, Peer D, Chen T, Yang L and Chen LL*. 2024. Therapeutic application of circular RNA aptamers in a mouse model of psoriasis. Nat Biotechnol, DOI:


  • 94. Shan L, Li P, Yu HT* and Chen LL*. 2023. Emerging roles of nuclear bodies in genome spatial organization. Trends Cell Biol, DOI:
  • 93. Sun JR, Yang LZ, Dai YL, Wu H, Li SQ, Xu YF, Huang YK, Wu H, Shen Z, Zou CC* and Chen LL*. 2023. Using sno-lncRNAs as potential markers for Prader-Willi syndrome diagnosis. RNA Biol, 20(1):419-430.
  • 92. Shan L, Xu G, Yao RW, Luan PF, Huang YK, Zhang PH, Pan YH, Zhang L, Gao X, Li Y, Cao SM, Gao SX, Yang ZH, Li SQ, Yang LZ, Wang Y, Wong CCL, Yu L, Li JS, Yang L and Chen LL. 2023. Nucleolar URB1 ensures 3′ ETS rRNA removal to prevent exosome surveillance. Nature, 615(7952):526-534.
  • 91. Chen LL, Bindereif A, Bozzoni I, Chang HY, Matera GA, Gorospe Y, Hansen TB, Kjems J, Ma XK, Pek JW, Rajewsky N, Salzman J, Wilusz JE, Yang L, and Zhao F. 2023. A guide to naming eukaryotic circular RNAs. Nat Cell Biol, 25(1):1-5.
  • 90. Mattick JS, Amaral PP, Carninci P, Carpenter S, Chang HY, Chen LL, Chen R, Dean C, Dinger ME, Fitzgerald KA, Gingeras TR, Guttman M, Hirose T, Huarte M, Johnson R, Kanduri C, Kapranov P, Lawrence JB, Lee JT, Mendell JT, Mercer TR, Moore KJ, Nakagawa S, Rinn JL, Spector DL, Ulitsky I, Wan Y, Wilusz JE, and Wu M. 2023. Long non-coding RNAs: Definitions, functions, challenges and recommendations. Nat Rev Mol Cell Biol, 24(6):430-447.
  • 89. Huang YK, Gao BQ, Meng Q, Yang LZ, Ma XK, Wu H, Pan YH, Yang L, Li D and Chen LL. 2023. CRISPR-dCas13-tracing reveals transcriptional memory and limited mRNA export in developing zebrafish embryos. Genome Biol, 24(1):15.
  • 88. Chen LL. 2023. Placing non-coding RNAs in the Central Dogma: An interview with Ling-Ling Chen. Mol Cell, 83(3):317-319.


  • 87. Chen LL. 2022. Towards higher-resolution and in vivo understanding of lncRNA biogenesis and function. Nat Methods,19(10):1152-1155.
  • 86. Wu H and Chen LL. 2022. 7S RNA is surveilling mitochondrial DNA transcription. Life Metab, 1(1):8-9.
  • 85. Yang LZ, Gao BQ, Huang YK, Wang Y, Yang L and Chen LL. 2022. Multi-color RNA imaging with CRISPR-Cas13b systems in living cells. Cell Insight, 1(4):100044.
    • Cover article
  • 84. Li SQ, Wu H and Chen LL. 2022. Screening circular RNAs with functional potential using the RfxCas13d/BSJ-gRNA system. Nat Protoc,17(9):2085-2107.
  • 83. Liu CX and Chen LL. 2022. Circular RNAs: Characterization, cellular roles, and applications. Cell,185(12):2016-2034.
  • 82. Yang L, Wilusz JE and Chen LL. 2022. Biogenesis and regulatory roles of circular RNAs. Annu Rev Cell Dev Biol, 38:263-289.
  • 81. Liu JQ*, Yang LZ and Chen LL. 2022. Understanding lncRNA–protein assemblies with imaging and single-molecule approaches. Curr Opin Genet Dev, 72:128-137.
  • 80. Liu CX, Guo SK, Nan F, Xu YF, Yang L and Chen LL. 2022. RNA circles with minimized immunogenicity as potent PKR inhibitors. Mol Cell, 82(2):420-434.
  • 79. Gao X, Ma XK, Li X, Li GW, Liu CX, Zhang J, Wang Y, Wei J, Chen J, Chen LL and Yang L. 2022. Knockout of circRNAs by base editing back-splice sites of circularized exons. Genome Biol, 23(1):16.


  • 78. Liu CX and Chen LL. 2021. Expanded regulation of circular RNA translation. Mol Cell, 81(20):4111-4113.
  • 77. Wu M, Yang LZ and Chen LL. 2021. Long noncoding RNA and protein abundance in lncRNPs. RNA, 27(12):1427-1440.
    • Mid-Career Research Awardee Review
  • 76. Li X, Zhang JL, Lei YN, Liu XQ, Xue W, Zhang Y, Nan F, Gao X, Zhang J, Wei J, Yang L and Chen LL. 2021. Linking circular intronic RNA degradation and function in transcription by RNase H1. Sci China Life Sci, 64(11):1795-1809.
    • Cover article
  • 75. Wu M, Xu G, Han C, Luan PF, Xing YH, Nan F, Yang LZ, Huang YK, Yang ZH, Shan L, Yang L, Liu JQ and Chen LL. 2021. lncRNA SLERT controls phase separation of FC/DFCs to facilitate Pol I transcription. Science, 373(6554):547-555.
    • Perspectives by Tomohiro Yamazaki and Tetsuro HiroseI, Science, 2021, Vol 373, Issue 6554.DOI: 10.1126/science.abj8350
    • Research highlights by Nat Cell Biol, 23, 927 (2021).
  • 74. Xu G, Wu M and Chen LL. 2021. LETN and NPM1 tango in human nucleoli. Cell Res, 31(6):609-610.
  • 73. Wang XW, Liu CX, Chen LL and Qiangfeng Cliff Zhang. 2021. RNA structure probing uncovers RNA structure-dependent biological functions. Nat Chem Biol,17(7):755-766.
  • 72. Yao RW, Luan PF and Chen LL. 2021. An optimized fixation method containing glyoxal and paraformaldehyde for imaging nuclear bodies. RNA, 27(6):725-733.
  • 71. Guo SK, Nan F, Liu CX, Yang L and Chen LL. 2021. Mapping circular RNA structures in living cells by SHAPE-MaP. Methods, 196:47-55.
  • 70. Statello L, Guo CJ, Chen LL and Huarte M. 2021. Gene regulation by long non-coding RNAs and its biological functions. Nat Rev Mol Cell Biol, 22(2):96-118.
  • 69. Li X and Chen LL. 2021. Genome-wide siRNA screen for trans-factors of circular RNA regulation. Bio-101: e1010820. DOI: 10.21769/BioProtoc.1010820.
  • 68. Li SQ, Li X, Xue W, Zhang L, Yang LZ, Cao SM, Lei YN, Liu CX, Guo SK, Shan L, Wu M, Tao X, Zhang JL, Gao X, Zhang J, Wei J, Li JS, Yang L and Chen LL. 2020. Screening for functional circular RNAs using the CRISPR-Cas13 system. Nat Methods, 18(1):51-59.
    • The Author Profile of this Month by Vivian Marx, Nat Methods, 2021,18:3
    • Research highlights by Nat Rev Genet, 2021, 22(2):68


  • 67. Guo CJ, Xu G and Chen LL. 2020. Mechanisms of Long Noncoding RNA Nuclear Retention. Trends Biochem Sci, 45(11):947-960.
  • 66. Wang Y and Chen LL. 2020. Organization and function of paraspeckles. Essays Biochem, 64(6):875-882.
  • 65. Chen LL. 2020. The expanding regulatory mechanisms and cellular functions of circular RNAs. Nat Rev Mol Cell Biol. 21(8):475-490.
  • 64. Guo CJ, Ma XK, Xing YH, Zheng CC, Xu YF, Shan L, Zhang J, Wang SH, Wang YM, Carmichael GG, Yang L and Chen LL. 2020. Distinct processing of lncRNAs contributes to non-conserved functions in stem cells. Cell, 181(3):621-636.
    • Preview by Sharma H and Carninci P, Cell, 2020, 181(3):512-514
  • 63. Ma XK, Guo CJ, Yang L and Chen LL. 2020. Altered processing of lncRNA in stem cells contributes to non-conserved functions. Chemistry of Life, 40(7): 985-991.
  • 62. Wang Y, Yang LZ and Chen LL. 2020. Protocol for Dynamic Imaging of RNA in Living Cells by CRISPR-Cas13 System. Star Protocols, Jun 3; 1(1):100037.
  • 61. Yang LZ, Wang Y and Chen LL. 2020. RNA imaging in living cells by CRISPR-Cas13 systems. Chemistry of Life, 40(1): 1-7.
    • Cover Article
  • 60. Seal RL, Chen LL, Griffiths-Jones S, Lowe TM, Mathews MB, O’ Reily D, Pierce AJ, Stadler PF, Ulitsky I, Wolin SL and Bruford EA. 2020. A guide to naming human non-coding RNA genes. EMBO J, 39(6):e103777.


  • 59. Yao RW, Liu CX and Chen LL. 2019. Linking RNA processing and function. Cold Spring Harb Symp Quant Biol, 84:67-82.
  • 58. Ma XK, Wang MR, Liu CX, Dong R, Carmichael GG, Chen LL and Yang L. 2019. CIRCexplorer3: A CLEAR pipeline for direct comparison of circular and linear RNA expression. Genomics Proteomics Bioinformatics,17(5):511–521.
  • 57. A Conversation with Ling-Ling Chen, interviewed by Steve Mao, Senior Editor at Science. 2019. Cold Spring Harb Symp Quant Biol, 84:262-263.
  • 56. Dong R, Ma XK, Chen LL and Yang L. 2019. Genome-Wide Annotation of circRNAs and Their Alternative Back-Splicing/Splicing with CIRCexplorer Pipeline. Methods Mol Biol, 1870:137–149.
  • 55. Yang LZ, Wang Y, Li SQ, Yao RW, Luan PF, Wu H, Gordon G. Carmichael, Chen LL. 2019. Dynamic Imaging of RNA in Living Cells by CRISPR-Cas13 Systems. Mol Cell, 76(6):981-997.
    • F1000 Prime recommendation
    • Spotlighted by Davis BJ and O’Connell MR, Mol Cell, 2020, 77:207-209
  • 54. Yao RW, Xu G, Wang Y, Shan L, Luan PF, Wang Y, Wu M, Yang LZ, Xing YH, Yang L, Chen LL. 2019. Nascent Pre-rRNA Sorting via Phase Separation Drives the Assembly of Dense Fibrillar Components in the Human Nucleolus. Mol Cell, 76(5):767-783. (Featured Article)
    • Featured Article and Issue highlights
    • Preview by Lafontaine DL, Mol Cell, 2019, 177(4):797-799
    • Research highlights by Nat Chem Biol, 2019, 15:1029
  • 53. Liu CX, Li X, Nan F and Chen LL. 2019. Circular RNAs in innate immunity. Chemistry of Life, 39(3):424-429.
  • 52. Liu CX, Li X, Nan F, Jiang S, Gao X, Guo SK, Xue W, Cui Y, Dong K, Ding H, Qu B, Zhou Z, Shen N, Yang L and Chen LL. 2019. Structure and Degradation of Circular RNAs Regulate PKR Activation in Innate Immunity. Cell, 177(4):865-880.
    • Preview by Wilusz JE, Cell, 2019, 177(4):797-799
    • Research Highlighted by: Nat Rev Immunol. 2019, 19:351
    • Research Highlighted by: Nat Rev Mol Cell Biol. 2019, 20:387
    • Research Highlighted by: Science. 2019, 364: 847
    • Research Highlighted by: Cell Bioscience. 2019, 9:43-45
    • Research Highlighted by: Bull Chin Acad Sci. 2019, 33:91-95.
    • Five Recommendations in F1000 Prime
    • News reports by Science News Magazine ( by LUPUS NEWS, Technologytimes, Medical Xpress
  • 51. Yao RW, Wang Y and Chen LL. 2019. Cellular functions of long noncoding RNAs. Nat Cell Biol, 21(5): 542-551.
    • Editorial by Nat Cell Biol, 2019, 21:535 (A focus on regulatory RNA)


  • 50.Wang Y, Hu SB, Wang MR, Yao RW, Wu D, Yang L, Chen LL. 2018. Genome-wide screening of NEAT1 regulators reveals cross-regulation between paraspeckles and mitochondria. Nat Cell Biol, 20(10):1145-1158.
    • News and Views by Fox AH, Nat Cell Biol, 2018, 20(10): 1108-1109
  • 49. Xing YH and Chen LL. 2018. Processing and roles of snoRNA-ended long noncoding RNAs. Crit Rev Biochem Mol Biol, 53(6):596-606
  • 48.Li X, Yang L and Chen LL. 2018. The Biogenesis, Functions, and Challenges of Circular RNAs. Mol Cell, 71(3):428-442.
  • 47. Xiang JF, Yang Q, Liu CX, Wu M, Chen LL and Yang L. 2018. N6-Methyladenosines Modulate A-to-I RNA Editing. Mol Cell, 69(1):126-135.


  • 46. Li X, Liu CX, Xue W, Zhang Y, Jiang S, Yin QF, Wei J, Yao RW, Yang L, Chen LL. 2017. Coordinated circRNA Biogenesis and Function with NF90/NF110 in Viral Infection. Mol Cell, 67(2):214-277.(Featured Article)
    • Free featured article
    • Highlighted by Editor's Note and Meet the Authors
    • Preview by Cadena CY and Hur S, Mol Cell, 2017, 67:163-164
  • 45. Xing YH, Yao RW, Zhang Y, Guo CJ, Jiang S, Xu G, Dong R, Yang L, Chen LL. 2017. SLERT regulates DDX21-rings associated with Pol I transcription. Cell, 169(4): 664-678.
    • Research highlights by Bull Chin Acad Sci, 2017, 31:152-155
  • 44. Yang L and Chen LL. 2017. Enhancing the RNA engineering toolkit. Science, 358(6366): 996-997.
  • 43.Wu H, Yang L, Chen LL. 2017. The Diversity of Long Noncoding RNAs and Their Generation. Trends Genet, 33(8):540-552.
  • 42. Liang D, Tatomer DC, Luo Z, Wu H, Yang L, Chen LL, Cherry S, Wilusz JE. 2017. The Output of Protein-Coding Genes Shifts to Circular RNAs When the Pre-mRNA Processing Machinery Is Limiting. Mol Cell, 68(5): 940-954.
  • 41. Yang Y, Fan X, Mao M, Song X, Wu P, Zhang Y, Jin Y, Yang Y, Chen LL, Wang Y, Wong CC, Xiao X, Wang Z. 2017. Extensive translation of circular RNAs driven by N6-methyladenosine. Cell Res, 27(5):626-641.
  • 40. Chen LL, Yang L. 2017. ALUternative Regulation for Gene Expression. Trends Cell Biol, 27(7):480-490.
  • 39. Dong R, Ma XK, Chen LL and Yang L. 2017. Increased complexity of circRNA expression during species evolution. RNA Biol, 14(8):1064-1074.
  • 38. Niu NN, Xiang JF, Yang Q, Wang LJ, Wei ZY, Chen LL, Yang L, Zhou WG. 2017. RNA-binding protein SAMD4 regulates skeleton development through translational inhibition of Mig6 expression. Cell Discov, 3(1):16050.
  • 37. Marie Anne O’ Donnell. 2017. People & Ideas Ling-Ling Chen: Shaping a career in RNA biology. J Cell Biol, 216(11):3426-3427.


  • 36. Wu H, Yin QF, Luo Z, Yao RW, Zheng CC, Zhang J, Xiang JF, Yang L, Chen LL. 2016. Unusual Processing Generates SPA LncRNAs that Sequester Multiple RNA Binding Proteins. Mol Cell, 64(3):534-548.
    • Cover story and Issue highlights
    • Preview by Li Y and Fox AH, Mol Cell, 2016, 64:435-437
  • 35. Chen LL. 2016. The biogenesis and emerging roles of circular RNAs. Nat Rev Mol Cell Biol, 17(4), 205-211.
  • 34. Chen LL, Claw KG, Ramachandran S. 2016. A two-fold challenge: the experience of women of color in genomics. Genome Biol, 17(1):210.
  • 33. Zhang Y, Xue W, Li X, Zhang J, Chen S, Zhang JL, Yang L# and Chen LL. 2016. The Biogenesis of Nascent Circular RNAs. Cell Rep, 15(3):611-624.
  • 32. Chen LL. 2016. Linking Long Noncoding RNA Localization and Function. Trends Biochem Sci, 41(9):761-772.
    • Series: Fresh Perspectives from Emerging Experts
  • 31. Hu SB, Yao RW, Chen LL. 2016. Shedding light on paraspeckle structure by super-resolution microscopy. J Cell Biol, 214(7):789-791.
  • 30. Xing YH, Bai ZQ, Liu CX, Hu SB, Ruan MH, Chen LL. 2016. Research progress of long noncoding RNA in China. IUBMB Life, 68(11):887-893.
  • 29. Zhang XO, Dong R, Zhang Y, Zhang JL, Luo Z, Zhang J, Chen LL and Yang L#. 2016. Diverse alternative back-splicing and alternative splicing landscape of circular RNAs. Genome Res, 26(9):1277-1287.
  • 28. Dong R, Zhang XO, Zhang Y, Ma XK, Chen LL and Yang L. 2016. CircRNA-derived pseudogenes. Cell Res, 26(6):747-750.
  • 27. Chen LL. 2016. Ling-Ling Chen: Linking Long Noncoding RNA Processing and Function to RNA Biology. Trends in Biochem Sci, 41(9):733-734.
  • 26. Zhang Y, Yang L and Chen LL. 2016. Characterization of Circular RNAs. Methods in Molecular Biology, 1402: 215-227(Book chapter)


  • 25. Yin QF, Hu SB, Xu YF, Yang L, Carmichael GG and Chen LL. 2015. SnoVectors for nuclear expression of RNA. Nucleic Acids Res, 43(1):e5.
  • 24. Chen LL and Yang L. 2014. Regulation of circRNA biogenesis. RNA Biol, 12(4), 381-388.
  • 23. Xiang JF, Yang L, Chen LL. 2015. The long noncoding RNA regulation at the MYC locus. Curr Opin Genet Dev, 33:41-48.
  • 22. Chen LL and Yang L. 2015. Gear up in circles. Mol Cell, 58(5):715-717.
  • 21. Hu SB, Xiang JF, Li X, Xu Y, Xue W, Huang M, Wong CC, Sagum CA, Bedford MT, Yang L, Cheng D, and Chen LL. 2015. Protein arginine methyltransferase CARM1 attenuates the paraspeckle-mediated nuclear retention of mRNAs containing IRAlus. Genes & Dev, 29(6): 630-645
    • Perspectives by Elbarbary RA and Maquat LE, Genes Dev, 2015, 29:687-689
    • Research highlights by Bull Chin Acad Sci, 2015, 29:108
  • 20. Chen T, Xiang JF, Zhu S, Chen S, Yin QF, Zhang XO, Zhang J, Feng H, Dong R, Li XJ, Yang L and Chen LL. 2015. ADAR1 is required for differentiation and neural induction by regulating microRNA processing in a catalytically independent manner. Cell Res, 25(4):459-476.
    • Highlighted by ESC&Ipsc NEWS
  • 19. Zhong CQ, Yin Q, Xie ZF, Bai MZ, Dong R, Tang W, Xing YH,Zhang HL, Yang SM, Chen LL, Bartolomei MS, Smith AF, Li DS, Yang L, Wu YX, Li JS. 2015. CRISPR-Cas9-Mediated Genetic Screening in Mice with Haploid Embryonic Stem Cells Carrying a Guide RNA Library. Cell Stem Cell, 17(2):221-232.
  • 18. Yin QF, Chen LL and Yang L. 2014. Fractionation of Non-polyadenylated and Ribosomal-free RNAs from Mammalian Cells. Methods Mol Biol, 1206: 69-80 (Book chapter)


  • 17. Zhang XO, Wang HB, Zhang Y, Lu X, Chen LL and Yang L. 2014. Complementary sequence-mediated exon circularization. Cell, 159(1): 134-147 (Featured Article)
    • Preview by Vicens Q and Westhof E, Cell, 2014,159:13-14
    • Research highlights by Nat Rev Genetics, 2014, 15:717
    • Research highlights by Bull Chin Acad Sci, 2014, 28:282-284
    • F1000 Prime recommendation
  • 16. Xiang JF, Yin QF, Chen T, Zhang Y, Zhang XO, Wu Z, Zhang S, Wang HB, Ge JH, Lu XH, Yang L and Chen LL. 2014. Human colorectal cancer-specific CCAT1-L lncRNA regulates long-range chromatin interactions in the MYC locus. Cell Res, 24(5):513-531.(Cover Article and Issue Highlight)
    • Research highlights by Younger ST and Rinn JL, Cell Res, 2014, 24:643-644
    • Research highlights by
    • Research highlights by Global Medical Discovery
    • Research highlights by National Science Review, 2015, 2:7-8
  • 15. Yang L and Chen LL. 2014. Microexons go big. Cell, 159(7):1488-1489.
  • 14. Zhang Y, Yang L and Chen LL. 2014. Life without A tail: new formats of long noncoding RNAs. Int J Biochem and Cell Biol, 54:338-349.
  • 13. Zhang XO, Yin QF, Wang HB, Zhang Y, Chen T, Zheng P, Lu X, Chen LL and Yang L. 2014. Species-specific alternative splicing leads to unique expression of sno-lncRNAs. BMC Genomics, 15(1): 287 (Highly Accessed)
    • Highly accessed; featured article in Biome
  • 12. Yang L and Chen LL. 2014. Competition of RNA splicing: line in or circle up. Sci China Life Sci, 57(12):1232-1233.
  • 11. Chen LL and Zhao JC. 2014. Functional analysi of long noncoding RNAs in development and diseases. Adv Exp Med Biol, 825:129-158.
  • 10. Chen LL. 2014. Scientific migration of junior scientists to China. Genome Biol, 15(6):119.
  • 9. Zhang XO, Yin QF, Chen LL and Yang L. 2014. Gene expression profiling of non-polyadenylated RNA-seq across species. Genomics Data, 2:237-41.
  • 8. Zhang Y, Wang HB and Chen LL. 2014. Circular RNAs: new noncoding RNAs emerging from genome 'dark matter'. Chemistry of Life, 34:428-433.


  • 7. Xiang JF, Yin QF and Chen LL. 2013. Long noncoding RNAs: regulatory molecules in mammalian cells. Chin J Cell Biology, 35:262-272.
  • 6. Zhang Y, Zhang XO, Chen T, Xiang JF, Yin QF, Xing YH, Zhu S, Yang L and Chen LL. 2013. Circular intronic long noncoding RNAs. Mol Cell, 51(6):792-806. (Issue Highlight)
    • Preview by Bolisetty MT and Graveley BR, Mol Cell, 2013, 51:705-706
    • Research highlights by Nature, 2013, 501:464
    • Research highlights by by Nature China, 2013, doi:10.1038
  • 5. Zhu S, Xiang JF, Tian C, Chen LL and Yang L. 2013. Prediction of constitutive A-to-I editing sites from human transcriptomes in the absence of genomic sequences. BMC Genomics,14(1):206. (Highly Accessed)


  • 4. Yin QF, Yang L,Zhang Y, Xiang JF, Wu YW, Carmichael GG and Chen LL. 2012. Long noncoding RNAs with snoRNA ends. Mol Cell, 48(2):219-230. (Cover Article and Issue Highlight)
    • Preview by McCann KL and Baserga SJ, Mol Cell, 2012, 48:155-7
    • Research highlights by Nat Rev Mol Cell Biol, 2012, 13:686
    • Five recommendations in F1000 Prime
    • News coverage in Foundation for Prader-Willi Research
    • Best of Molecular Cell 2012
  • 3. Chen LL# and Carmichael GG. 2012. Nuclear editing of mRNA 3'-UTRs. Curr Top Microbiol Immunol, 353:111-121.


  • 2. Peng S, Chen LL#, Lei XX, Yang L, Lin H, Carmichael GG, Huang Y. 2011. Genome-wide studies reveal that Lin28 enhances the translation of genes important for growth and survival of human embryonic stem cells. Stem Cells, 29(3):496-504.
  • 1. Yang L, Duff MO, Graveley BR, Carmichael GG and Chen LL#. 2011. Genomewide characterization of non-polyadenylated RNAs. Genome Biol, 12(2):R16.
    • Editor's pick and highly accessed

Selected publications before Chen Lab:

  • Chen LL# and Carmichael GG#. 2010. Decoding the function of nuclear long non-coding RNAs. Curr Opin Cell Biol, 22: 357-364.
  • Chen LL#, Yang L and Carmichael GG#. 2010. Molecular basis for an attenuated cytoplasmic dsRNA response in human embryonic stem cells. Cell Cycle, 9:3552-3564.
    • News & Views
    • Preview by Williams BRG. Cell Cycle, (2010) 35:3400
  • Chen LL# and Carmichael GG. 2010. Long non-coding RNAs in mammalian cells: What, Where and Why? WIREs RNA, 1: 2-21.
  • Chen LL and Carmichael GG. 2009. Altered nuclear retention of mRNAs containing inverted repeats in human embryonic stem cells: functional role of a nuclear noncoding RNA. Mol Cell, 35: 467-478.
    • Preview by: Scadden D. (2009) Mol Cell, 35:395-396
    • Recommended in F1000 Prime
  • Chen LL and Carmichael GG. 2008. Gene regulation by SINES and inosines: biological consequences of A-to-I editing of Alu element inverted repeats. Cell Cycle, 7: 3297-3301.
  • Chen LL, Decerbo JN and Carmichael GG. 2008. Alu element-mediated gene silencing. EMBO J, 27: 1694-1705.

Powered by UIKit and Flask.

Copyright 2015-2020 Chen Lab (SIBCB, SIBS, CAS). All rights reserved.